3u5y: Difference between revisions

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'''Unreleased structure'''


The entry 3u5y is ON HOLD
==Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity==
<StructureSection load='3u5y' size='340' side='right'caption='[[3u5y]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3u5y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U5Y FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SCG:METHYL+(2S,3R,4S)-2-(BETA-D-GLUCOPYRANOSYLOXY)-4-(2-OXOETHYL)-3-VINYL-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE'>SCG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u5y OCA], [https://pdbe.org/3u5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u5y RCSB], [https://www.ebi.ac.uk/pdbsum/3u5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u5y ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RG1_RAUSE RG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the treatment of heart disorders.<ref>PMID:10975500</ref>


Authors: Liqun Xia, Martin Ruppert, Meitian Wang, Santosh Panjikar, Leif Barleben, Chitra Rajendran, Haili Lin, Joachim St ckigt
==See Also==
 
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
Description: Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rauvolfia serpentina]]
[[Category: Barleben L]]
[[Category: Lin H]]
[[Category: Panjikar S]]
[[Category: Rajendran C]]
[[Category: Ruppert M]]
[[Category: Stoeckigt J]]
[[Category: Wang M]]
[[Category: Xia L]]