3tsi: Difference between revisions

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[[Image:3tsi.png|left|200px]]


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==Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain==
The line below this paragraph, containing "STRUCTURE_3tsi", creates the "Structure Box" on the page.
<StructureSection load='3tsi' size='340' side='right'caption='[[3tsi]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3tsi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Simian_virus_5_(strain_W3) Simian virus 5 (strain W3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.651&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsi OCA], [https://pdbe.org/3tsi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsi RCSB], [https://www.ebi.ac.uk/pdbsum/3tsi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsi ProSAT]</span></td></tr>
{{STRUCTURE_3tsi|  PDB=3tsi  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/HN_PIV5 HN_PIV5] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity).  Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.


===Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain===
==See Also==
 
*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_21994464}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 21994464 is the PubMed ID number.
[[Category: Bose S]]
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[[Category: Jardetzky TS]]
{{ABSTRACT_PUBMED_21994464}}
[[Category: Kors CA]]
 
[[Category: Lamb RA]]
==About this Structure==
[[Category: Welch BD]]
[[3tsi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Parainfluenza_virus_5 Parainfluenza virus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSI OCA].
[[Category: Yuan P]]
 
==Reference==
<ref group="xtra">PMID:021994464</ref><references group="xtra"/>
[[Category: Exo-alpha-sialidase]]
[[Category: Parainfluenza virus 5]]
[[Category: Bose, S.]]
[[Category: Jardetzky, T S.]]
[[Category: Kors, C A.]]
[[Category: Lamb, R A.]]
[[Category: Welch, B D.]]
[[Category: Yuan, P.]]
[[Category: 11-mer hydrophobic repeat]]
[[Category: Ectodomain]]
[[Category: Four stranded coiled coil]]
[[Category: Four-helix bundle]]
[[Category: Receptor binding protein]]
[[Category: Viral protein]]
Retrieved from "https://proteopedia.org/3tsi"