3swh: Difference between revisions

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[[Image:3swh.jpg|left|200px]]


<!--
==Munc13-1, MUN domain, C-terminal module==
The line below this paragraph, containing "STRUCTURE_3swh", creates the "Structure Box" on the page.
<StructureSection load='3swh' size='340' side='right'caption='[[3swh]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3swh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SWH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3swh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3swh OCA], [https://pdbe.org/3swh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3swh RCSB], [https://www.ebi.ac.uk/pdbsum/3swh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3swh ProSAT]</span></td></tr>
{{STRUCTURE_3swh|  PDB=3swh  |  SCENE=  }}
</table>
 
== Function ==
===Munc13-1, MUN domain, C-terminal module===
[https://www.uniprot.org/uniprot/UN13A_RAT UN13A_RAT] Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. Also involved in secretory granule priming in insulin secretion.<ref>PMID:9697857</ref> <ref>PMID:11343654</ref> <ref>PMID:11792326</ref>  
 
== References ==
 
<references/>
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__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_22000513}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 22000513 is the PubMed ID number.
[[Category: Large Structures]]
-->
{{ABSTRACT_PUBMED_22000513}}
 
==About this Structure==
[[3swh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SWH OCA].  
 
==Reference==
<ref group="xtra">PMID:022000513</ref><ref group="xtra">PMID:021499244</ref><references group="xtra"/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Li, W.]]
[[Category: Li W]]
[[Category: Rizo, J.]]
[[Category: Rizo J]]
[[Category: Tomchick, D R.]]
[[Category: Tomchick DR]]
[[Category: Alpha helical]]
[[Category: Exocytosis]]
[[Category: Neurotransmitter release]]
[[Category: Snare motif]]
Retrieved from "https://proteopedia.org/3swh"