3tsz: Difference between revisions

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[[Image:3tsz.png|left|200px]]


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==crystal structure of PDZ3-SH3-GUK core module from human ZO-1 in complex with 12mer peptide from human JAM-A cytoplasmic tail==
The line below this paragraph, containing "STRUCTURE_3tsz", creates the "Structure Box" on the page.
<StructureSection load='3tsz' size='340' side='right'caption='[[3tsz]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3tsz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSZ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.502&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsz OCA], [https://pdbe.org/3tsz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsz RCSB], [https://www.ebi.ac.uk/pdbsum/3tsz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsz ProSAT]</span></td></tr>
{{STRUCTURE_3tsz|  PDB=3tsz  |  SCENE=  }}
</table>
 
== Function ==
===crystal structure of PDZ3-SH3-GUK core module from human ZO-1 in complex with 12mer peptide from human JAM-A cytoplasmic tail===
[https://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref>  
 
== References ==
 
<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_22030391}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 22030391 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_22030391}}
 
==About this Structure==
[[3tsz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSZ OCA].  
 
==Reference==
<ref group="xtra">PMID:022030391</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lavie, A.]]
[[Category: Large Structures]]
[[Category: Nomme, J.]]
[[Category: Lavie A]]
[[Category: Cell adhesion]]
[[Category: Nomme J]]
[[Category: Jam]]
[[Category: Pdz3-sh3-guk]]
[[Category: Scaffolding]]
[[Category: Tight junction]]

Latest revision as of 13:38, 14 March 2024

crystal structure of PDZ3-SH3-GUK core module from human ZO-1 in complex with 12mer peptide from human JAM-A cytoplasmic tail

3tsz, resolution 2.50Å

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