3ksn: Difference between revisions

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[[Image:3ksn.png|left|200px]]


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==Crystal structure of the lipoprotein localization factor, LolA==
The line below this paragraph, containing "STRUCTURE_3ksn", creates the "Structure Box" on the page.
<StructureSection load='3ksn' size='340' side='right'caption='[[3ksn]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ksn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KSN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ksn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ksn OCA], [https://pdbe.org/3ksn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ksn RCSB], [https://www.ebi.ac.uk/pdbsum/3ksn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ksn ProSAT]</span></td></tr>
{{STRUCTURE_3ksn|  PDB=3ksn  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of the lipoprotein localization factor, LolA===
[https://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref>  May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
[[3ksn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KSN OCA].  
  <jmolCheckbox>
[[Category: Escherichia coli]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/3ksn_consurf.spt"</scriptWhenChecked>
[[Category: Ahmadpour, F.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Brown, E D.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Gloyd, M.]]
  </jmolCheckbox>
[[Category: Guarne, A.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ksn ConSurf].
[[Category: Pathania, R.]]
<div style="clear:both"></div>
[[Category: Stewart, G.]]
== References ==
[[Category: Chaperone]]
<references/>
[[Category: Lipoprotein carrier]]
__TOC__
[[Category: Protein transport]]
</StructureSection>
[[Category: Transport]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Ahmadpour F]]
[[Category: Brown ED]]
[[Category: Gloyd M]]
[[Category: Guarne A]]
[[Category: Pathania R]]
[[Category: Stewart G]]