3t6g: Difference between revisions

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[[Image:3t6g.jpg|left|200px]]


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==Structure of the complex between NSP3 (SHEP1) and p130Cas==
The line below this paragraph, containing "STRUCTURE_3t6g", creates the "Structure Box" on the page.
<StructureSection load='3t6g' size='340' side='right'caption='[[3t6g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3t6g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T6G FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
{{STRUCTURE_3t6g|  PDB=3t6g  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t6g OCA], [https://pdbe.org/3t6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t6g RCSB], [https://www.ebi.ac.uk/pdbsum/3t6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t6g ProSAT]</span></td></tr>
 
</table>
===Structure of the complex between NSP3 (SHEP1) and p130Cas===
== Function ==
 
[https://www.uniprot.org/uniprot/SH2D3_HUMAN SH2D3_HUMAN] Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity).
 
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{{ABSTRACT_PUBMED_22081014}}
 
==About this Structure==
[[3t6g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6G OCA].  
 
==Reference==
<ref group="xtra">PMID:022081014</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mace, P D.]]
[[Category: Large Structures]]
[[Category: Riedl, S J.]]
[[Category: Mace PD]]
[[Category: Robinson, H.]]
[[Category: Riedl SJ]]
[[Category: Cdc25-homology domain]]
[[Category: Robinson H]]
[[Category: Cell adhesion]]
[[Category: Focal-adhesion targeting domain]]
[[Category: Gtpase exchange factor]]
[[Category: Signaling protein]]