3u96: Difference between revisions
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The | ==Crystal Structure of YopHQ357F(Catalytic Domain, Residues 163-468) in complex with pNCS== | ||
<StructureSection load='3u96' size='340' side='right'caption='[[3u96]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3u96]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U96 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSN:N,4-DIHYDROXY-N-OXO-3-(SULFOOXY)BENZENAMINIUM'>CSN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u96 OCA], [https://pdbe.org/3u96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u96 RCSB], [https://www.ebi.ac.uk/pdbsum/3u96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u96 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/YOPH_YEREN YOPH_YEREN] Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages. | |||
==See Also== | |||
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Yersinia enterocolitica]] | |||
[[Category: Ho MC]] | |||
[[Category: Ke S]] | |||
Latest revision as of 08:38, 20 March 2024
Crystal Structure of YopHQ357F(Catalytic Domain, Residues 163-468) in complex with pNCS
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