3sza: Difference between revisions

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[[Image:3sza.png|left|200px]]


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==Crystal structure of human ALDH3A1 - apo form==
The line below this paragraph, containing "STRUCTURE_3sza", creates the "Structure Box" on the page.
<StructureSection load='3sza' size='340' side='right'caption='[[3sza]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3sza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SZA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
{{STRUCTURE_3sza|  PDB=3sza  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sza OCA], [https://pdbe.org/3sza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sza RCSB], [https://www.ebi.ac.uk/pdbsum/3sza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sza ProSAT]</span></td></tr>
 
</table>
===Crystal structure of human ALDH3A1 - apo form===
== Function ==
 
[https://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
 
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{{ABSTRACT_PUBMED_22021038}}
 
==About this Structure==
[[3sza]] is a 2 chain structure of [[Aldehyde dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SZA OCA].  


==See Also==
==See Also==
*[[Aldehyde dehydrogenase]]
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022021038</ref><ref group="xtra">PMID:018647600</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hurley, T D.]]
[[Category: Large Structures]]
[[Category: Khanna, M.]]
[[Category: Hurley TD]]
[[Category: Aldh]]
[[Category: Khanna M]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]