3v71: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 3v71 is ON HOLD until Paper Publication Authors: Qiu, C., Kershner, A., Wang, Y., Holley, C.H., Wilinski, D., Keles, S., Kimble, J., Wickens, M., Ha... |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of PUF-6 in complex with 5BE13 RNA== | |||
<StructureSection load='3v71' size='340' side='right'caption='[[3v71]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V71 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.902Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v71 OCA], [https://pdbe.org/3v71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v71 RCSB], [https://www.ebi.ac.uk/pdbsum/3v71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v71 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PUF7_CAEEL PUF7_CAEEL] RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-5 and puf-6 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.<ref>PMID:17234175</ref> <ref>PMID:22205700</ref> <ref>PMID:22542599</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Caenorhabditis elegans]] | |||
[[Category: Large Structures]] | |||
[[Category: Hall TMT]] | |||
[[Category: Holley CH]] | |||
[[Category: Keles S]] | |||
[[Category: Kershner A]] | |||
[[Category: Kimble J]] | |||
[[Category: Qiu C]] | |||
[[Category: Wang Y]] | |||
[[Category: Wickens M]] | |||
[[Category: Wilinski D]] | |||
Latest revision as of 14:19, 14 March 2024
Crystal structure of PUF-6 in complex with 5BE13 RNA
| ||||||||||||