3uin: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3uin.jpg|left|200px]]


<!--
==Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2==
The line below this paragraph, containing "STRUCTURE_3uin", creates the "Structure Box" on the page.
<StructureSection load='3uin' size='340' side='right'caption='[[3uin]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3uin]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UIN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.597&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uin OCA], [https://pdbe.org/3uin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uin RCSB], [https://www.ebi.ac.uk/pdbsum/3uin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uin ProSAT]</span></td></tr>
{{STRUCTURE_3uin|  PDB=3uin  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/UBC9_HUMAN UBC9_HUMAN] Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation.<ref>PMID:8668529</ref> <ref>PMID:11451954</ref> <ref>PMID:15809060</ref> <ref>PMID:19744555</ref> <ref>PMID:19638400</ref> <ref>PMID:17466333</ref> <ref>PMID:20077568</ref>  


===Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2===
==See Also==
 
*[[SUMO 3D Structures|SUMO 3D Structures]]
 
*[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]]
<!--
== References ==
The line below this paragraph, {{ABSTRACT_PUBMED_22194619}}, adds the Publication Abstract to the page
<references/>
(as it appears on PubMed at http://www.pubmed.gov), where 22194619 is the PubMed ID number.
__TOC__
-->
</StructureSection>
{{ABSTRACT_PUBMED_22194619}}
 
==About this Structure==
[[3uin]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UIN OCA].
 
==Reference==
<ref group="xtra">PMID:022194619</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Gareau, J R.]]
[[Category: Large Structures]]
[[Category: Lima, C D.]]
[[Category: Gareau JR]]
[[Category: Reverter, D.]]
[[Category: Lima CD]]
[[Category: E3]]
[[Category: Reverter D]]
[[Category: Ligase]]
[[Category: Ligase-isomerase-protein binding complex]]
[[Category: Nuclear pore complex]]
[[Category: Ranbp2]]
[[Category: Sumo]]
[[Category: Ubc9]]