3uby: Difference between revisions

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[[Image:3uby.png|left|200px]]


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==Crystal structure of human alklyadenine DNA glycosylase in a lower and higher-affinity complex with DNA==
The line below this paragraph, containing "STRUCTURE_3uby", creates the "Structure Box" on the page.
<StructureSection load='3uby' size='340' side='right'caption='[[3uby]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3uby]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UBY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDC:N3,N4-ETHENO-2-DEOXYCYTIDINE-5-MONOPHOSPHATE'>EDC</scene></td></tr>
{{STRUCTURE_3uby|  PDB=3uby  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uby OCA], [https://pdbe.org/3uby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uby RCSB], [https://www.ebi.ac.uk/pdbsum/3uby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uby ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/3MG_HUMAN 3MG_HUMAN] Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.


===Crystal structure of human alklyadenine DNA glycosylase in a lower and higher-affinity complex with DNA===
==See Also==
 
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
 
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</StructureSection>
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{{ABSTRACT_PUBMED_22148158}}
 
==About this Structure==
[[3uby]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UBY OCA].
 
==Reference==
<ref group="xtra">PMID:022148158</ref><references group="xtra"/>
[[Category: DNA-3-methyladenine glycosylase II]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Davis, C A.]]
[[Category: Large Structures]]
[[Category: Drennan, C L.]]
[[Category: Davis CA]]
[[Category: Lingaraju, G M.]]
[[Category: Drennan CL]]
[[Category: Samson, L D.]]
[[Category: Lingaraju GM]]
[[Category: Setser, J W.]]
[[Category: Samson LD]]
[[Category: Aag]]
[[Category: Setser JW]]
[[Category: Alkyladenine dna glycosylase fold]]
[[Category: Dna binding]]
[[Category: Dna repair]]
[[Category: Hydrolase-dna complex]]
[[Category: Nucleus]]
Retrieved from "https://proteopedia.org/3uby"