4af8: Difference between revisions
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The | ==The structural basis for metacaspase substrate specificity and activation== | ||
<StructureSection load='4af8' size='340' side='right'caption='[[4af8]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4af8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AF8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4af8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4af8 OCA], [https://pdbe.org/4af8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4af8 RCSB], [https://www.ebi.ac.uk/pdbsum/4af8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4af8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MCA2_TRYB2 MCA2_TRYB2] Cysteine protease that cleaves specifically after arginine or lysine residues.<ref>PMID:18005666</ref> <ref>PMID:23506317</ref> | |||
==See Also== | |||
*[[Caspase 3D structures|Caspase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Trypanosoma brucei]] | |||
[[Category: Coombs GH]] | |||
[[Category: Isaacs NW]] | |||
[[Category: McLuskey K]] | |||
[[Category: Moss CX]] | |||
[[Category: Mottram JC]] | |||
[[Category: Rudolf J]] | |||
Latest revision as of 07:14, 1 May 2024
The structural basis for metacaspase substrate specificity and activation
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