4dex: Difference between revisions
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New page: '''Unreleased structure''' The entry 4dex is ON HOLD Authors: Almagor, L., Hirsch, J.A. Description: Crystal structure of the Voltage Dependent Calcium Channel beta-2 Subunit in Comple... |
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The | ==Crystal structure of the Voltage Dependent Calcium Channel beta-2 Subunit in Complex With The CaV2.2 I-II Linker.== | ||
<StructureSection load='4dex' size='340' side='right'caption='[[4dex]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4dex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DEX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dex OCA], [https://pdbe.org/4dex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dex RCSB], [https://www.ebi.ac.uk/pdbsum/4dex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dex ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CACB2_RABIT CACB2_RABIT] The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. | |||
==See Also== | |||
*[[Ion channels 3D structures|Ion channels 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Almagor L]] | |||
[[Category: Hirsch JA]] | |||
