2e46: Difference between revisions

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[[Image:2e46.jpg|left|200px]]<br /><applet load="2e46" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2e46, resolution 2.30&Aring;" />
'''Crystal Structure Analysis of the clock protein EA4'''<br />


==About this Structure==
==Crystal Structure Analysis of the clock protein EA4==
2E46 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori] with <scene name='pdbligand=CU:'>CU</scene> and <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Cu+Binding+Site+For+Residue+A+171'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+172'>AC2</scene> and <scene name='pdbsite=AC3:Cu+Binding+Site+For+Residue+A+181'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E46 OCA].  
<StructureSection load='2e46' size='340' side='right'caption='[[2e46]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2e46]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E46 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e46 OCA], [https://pdbe.org/2e46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e46 RCSB], [https://www.ebi.ac.uk/pdbsum/2e46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e46 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q08J22_BOMMO Q08J22_BOMMO] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000393]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e4/2e46_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e46 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bombyx mori]]
[[Category: Bombyx mori]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hiraki, T.]]
[[Category: Hiraki T]]
[[Category: Park, S.Y.]]
[[Category: Park S-Y]]
[[Category: CU]]
[[Category: ZN]]
[[Category: metal binding protein]]
[[Category: metalloprotein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb  6 17:21:31 2008''

Latest revision as of 07:56, 30 October 2024

Crystal Structure Analysis of the clock protein EA4

2e46, resolution 2.30Å

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