4dog: Difference between revisions
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==Structures of Vaccinia Virus Uracil-DNA Glycosylase in New Crystal Forms== | |||
<StructureSection load='4dog' size='340' side='right'caption='[[4dog]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4dog]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Western_Reserve Vaccinia virus Western Reserve]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DOG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dog OCA], [https://pdbe.org/4dog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dog RCSB], [https://www.ebi.ac.uk/pdbsum/4dog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dog ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UNG_VACCW UNG_VACCW] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity). | |||
==See Also== | |||
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Vaccinia virus Western Reserve]] | |||
[[Category: Chattopadhyay D]] | |||
[[Category: Schormann N]] | |||
Latest revision as of 14:40, 14 March 2024
Structures of Vaccinia Virus Uracil-DNA Glycosylase in New Crystal Forms
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