3v69: Difference between revisions

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[[Image:3v69.jpg|left|200px]]


<!--
==Filia-N crystal structure==
The line below this paragraph, containing "STRUCTURE_3v69", creates the "Structure Box" on the page.
<StructureSection load='3v69' size='340' side='right'caption='[[3v69]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3v69]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V69 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V69 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v69 OCA], [https://pdbe.org/3v69 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v69 RCSB], [https://www.ebi.ac.uk/pdbsum/3v69 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v69 ProSAT]</span></td></tr>
{{STRUCTURE_3v69|  PDB=3v69  |  SCENE=  }}
</table>
 
== Function ==
===Filia-N crystal structure===
[https://www.uniprot.org/uniprot/KHDC3_MOUSE KHDC3_MOUSE] Required for maintenance of euploidy during cleavage-stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function. Capable of binding RNA.<ref>PMID:19376971</ref> <ref>PMID:22276159</ref>
 
== References ==
 
<references/>
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__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_22276159}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 22276159 is the PubMed ID number.
[[Category: Large Structures]]
-->
{{ABSTRACT_PUBMED_22276159}}
 
==About this Structure==
[[3v69]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V69 OCA].  
 
==Reference==
<ref group="xtra">PMID:022276159</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Li, L.]]
[[Category: Li L]]
[[Category: Liu, X.]]
[[Category: Liu X]]
[[Category: Wang, J.]]
[[Category: Wang J]]
[[Category: Xu, M.]]
[[Category: Xu M]]
[[Category: Zhu, K.]]
[[Category: Zhu K]]
[[Category: Embryogenesis]]
[[Category: Filia]]
[[Category: Kh domain]]
[[Category: Protein binding]]
[[Category: Rna binding]]
[[Category: Rna-binding]]

Latest revision as of 08:39, 20 March 2024

Filia-N crystal structure

3v69, resolution 2.20Å

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