3nj2: Difference between revisions
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< | ==Crystal structure of cce_0566 from the cyanobacterium Cyanothece 51142, a protein associated with nitrogen fixation from the DUF269 family== | ||
<StructureSection load='3nj2' size='340' side='right'caption='[[3nj2]], [[Resolution|resolution]] 1.59Å' scene=''> | |||
You may | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3nj2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crocosphaera_subtropica_ATCC_51142 Crocosphaera subtropica ATCC 51142]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NJ2 FirstGlance]. <br> | |||
or | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59Å</td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nj2 OCA], [https://pdbe.org/3nj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nj2 RCSB], [https://www.ebi.ac.uk/pdbsum/3nj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nj2 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/B1WPD5_CROS5 B1WPD5_CROS5] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nj/3nj2_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nj2 ConSurf]. | |||
<div style="clear:both"></div> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The crystal structure for cce_0566 (171 aa, 19.4kDa), a DUF269 annotated protein from the diazotrophic cyanobacterium Cyanothece sp. ATCC 51142, was determined to 1.60A resolution. Cce_0566 is a homodimer with each molecule composed of eight alpha-helices folded on one side of a three strand anti-parallel beta-sheet. Hydrophobic interactions between the side chains of largely conserved residues on the surface of each beta-sheet hold the dimer together. The fold observed for cce_0566 may be unique to proteins in the DUF269 family, hence, the protein may also have a function unique to nitrogen fixation. A solvent accessible cleft containing conserved charged residues near the dimer interface could represent the active site or ligand-binding surface for the protein's biological function. STRUCTURED SUMMARY OF PROTEIN INTERACTIONS: DUF269 and DUF269bind by x-ray crystallography (View interaction). | |||
Crystal structure of cce_0566 from Cyanothece 51142, a protein associated with nitrogen fixation in the DUF269 family.,Buchko GW, Robinson H FEBS Lett. 2012 Feb 17;586(4):350-5. Epub 2012 Jan 28. PMID:22289180<ref>PMID:22289180</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 3nj2" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
== | [[Category: Crocosphaera subtropica ATCC 51142]] | ||
[[Category: Large Structures]] | |||
[[Category: Addlagatta A]] | |||
== | [[Category: Buchko GW]] | ||
< | [[Category: Ralston CY]] | ||
[[Category: | [[Category: Robinson H]] | ||
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Latest revision as of 09:16, 6 September 2023
Crystal structure of cce_0566 from the cyanobacterium Cyanothece 51142, a protein associated with nitrogen fixation from the DUF269 family
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