4drz: Difference between revisions

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==Crystal structure of human RAB14==
The line below this paragraph, containing "STRUCTURE_4drz", creates the "Structure Box" on the page.
<StructureSection load='4drz' size='340' side='right'caption='[[4drz]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4drz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2aed 2aed]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DRZ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
{{STRUCTURE_4drz|  PDB=4drz  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4drz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drz OCA], [https://pdbe.org/4drz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4drz RCSB], [https://www.ebi.ac.uk/pdbsum/4drz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4drz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAB14_HUMAN RAB14_HUMAN] Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.<ref>PMID:22595670</ref>  


===Crystal structure of human RAB14===
==See Also==
 
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
 
== References ==
==About this Structure==
<references/>
[[4drz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2aed 2aed]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRZ OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bochkarev, A.]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A M.]]
[[Category: Bochkarev A]]
[[Category: Park, H.]]
[[Category: Edwards AM]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Sundstrom, M.]]
[[Category: Sundstrom M]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Wang, J.]]
[[Category: Wang J]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Gtp]]
[[Category: Gtpase]]
[[Category: Oncogene]]
[[Category: Protein transport]]
[[Category: Rab14]]
[[Category: Ra]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
Retrieved from "https://proteopedia.org/4drz"