4dy1: Difference between revisions

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'''Unreleased structure'''


The entry 4dy1 is ON HOLD
==tRNA-guanine transglycosylase F92C C158S C281S mutant==
<StructureSection load='4dy1' size='340' side='right'caption='[[4dy1]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dy1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DY1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.045&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dy1 OCA], [https://pdbe.org/4dy1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dy1 RCSB], [https://www.ebi.ac.uk/pdbsum/4dy1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dy1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]


Authors: Jakobi, S., Heine, A., Klebe, G.
==See Also==
 
*[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]]
Description: tRNA-guanine transglycosylase F92C C158S C281S mutant
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Zymomonas mobilis]]
[[Category: Heine A]]
[[Category: Jakobi S]]
[[Category: Klebe G]]
Retrieved from "https://proteopedia.org/4dy1"