3to8: Difference between revisions

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[[Image:3to8.jpg|left|200px]]


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==Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L)==
The line below this paragraph, containing "STRUCTURE_3to8", creates the "Structure Box" on the page.
<StructureSection load='3to8' size='340' side='right'caption='[[3to8]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3to8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TO8 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3to8|  PDB=3to8  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3to8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3to8 OCA], [https://pdbe.org/3to8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3to8 RCSB], [https://www.ebi.ac.uk/pdbsum/3to8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3to8 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L)===
== Function ==
 
[https://www.uniprot.org/uniprot/HNRPL_HUMAN HNRPL_HUMAN] Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.<ref>PMID:11809897</ref>
 
== References ==
==About this Structure==
<references/>
[[3to8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TO8 OCA].  
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Li, X.]]
[[Category: Large Structures]]
[[Category: Liu, Y W.]]
[[Category: Li X]]
[[Category: Niu, L W.]]
[[Category: Liu YW]]
[[Category: Teng, M K.]]
[[Category: Niu LW]]
[[Category: Zeng, F X.]]
[[Category: Teng MK]]
[[Category: Zhang, W J.]]
[[Category: Zeng FX]]
[[Category: Zhao, Y.]]
[[Category: Zhang WJ]]
[[Category: Rna binding protein]]
[[Category: Zhao Y]]
[[Category: Rna recognition motif]]
[[Category: Splicing]]
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