4e18: Difference between revisions
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New page: '''Unreleased structure''' The entry 4e18 is ON HOLD until Paper Publication Authors: Choi, H.-J., Pokutta, S., Cadwell, G.W., Bankston, L.A., Liddington, R.C., Weis, W.I. Description:... |
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==Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin== | |||
<StructureSection load='4e18' size='340' side='right'caption='[[4e18]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4e18]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E18 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.403Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e18 OCA], [https://pdbe.org/4e18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e18 RCSB], [https://www.ebi.ac.uk/pdbsum/4e18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e18 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> | |||
==See Also== | |||
*[[Catenin 3D structures|Catenin 3D structures]] | |||
*[[Vinculin|Vinculin]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Gallus gallus]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Bankston LA]] | |||
[[Category: Cadwell GW]] | |||
[[Category: Choi H-J]] | |||
[[Category: Liddington RC]] | |||
[[Category: Pokutta S]] | |||
[[Category: Weis WI]] | |||
Latest revision as of 14:49, 14 March 2024
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
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