3lnr: Difference between revisions

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[[Image:3lnr.png|left|200px]]


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==Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2==
The line below this paragraph, containing "STRUCTURE_3lnr", creates the "Structure Box" on the page.
<StructureSection load='3lnr' size='340' side='right'caption='[[3lnr]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3lnr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LNR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
{{STRUCTURE_3lnr|  PDB=3lnr  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lnr OCA], [https://pdbe.org/3lnr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lnr RCSB], [https://www.ebi.ac.uk/pdbsum/3lnr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lnr ProSAT]</span></td></tr>
 
</table>
===Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2===
== Function ==
 
[https://www.uniprot.org/uniprot/MCPB_PSEAE MCPB_PSEAE] Chemoreceptor that plays a critical role in the virulence and pathogenesis of P.aeruginosa in a variety of hosts (PubMed:31511598). Probably acts through oxygen sensing (PubMed:31511598, PubMed:28167524, PubMed:34383467). Uses a heme-based sensor (PubMed:21255112, PubMed:22622145). Could be involved in chemotaxis (PubMed:12142407, PubMed:14987771). When expressed in E.coli, is able to sense and mediate repellent responses to oxygen, carbon monoxide and nitric oxide (PubMed:21255112).<ref>PMID:12142407</ref> <ref>PMID:14987771</ref> <ref>PMID:21255112</ref> <ref>PMID:22622145</ref> <ref>PMID:28167524</ref> <ref>PMID:31511598</ref> <ref>PMID:34383467</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_20399181}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ln/3lnr_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_20399181}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[3lnr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNR OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lnr ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:020399181</ref><references group="xtra"/>
<references/>
[[Category: Pseudomonas aeruginosa]]
__TOC__
[[Category: Airola, M V.]]
</StructureSection>
[[Category: Bilwes, A M.]]
[[Category: Large Structures]]
[[Category: Crane, B R.]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Hamp domain]]
[[Category: Airola MV]]
[[Category: Poly-hamp domain]]
[[Category: Bilwes AM]]
[[Category: Signaling protein]]
[[Category: Crane BR]]

Latest revision as of 10:21, 21 February 2024

Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2

3lnr, resolution 2.64Å

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