3sx7: Difference between revisions

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[[Image:3sx7.png|left|200px]]


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==Crystal structure of ABBA+UDP+Gal with Glycerol as the cryoprotectant==
The line below this paragraph, containing "STRUCTURE_3sx7", creates the "Structure Box" on the page.
<StructureSection load='3sx7' size='340' side='right'caption='[[3sx7]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3sx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SX7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
{{STRUCTURE_3sx7|  PDB=3sx7  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sx7 OCA], [https://pdbe.org/3sx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sx7 RCSB], [https://www.ebi.ac.uk/pdbsum/3sx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sx7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.


===Crystal structure of ABBA+UDP+Gal with Glycerol as the cryoprotectant===
==See Also==
 
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
 
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</StructureSection>
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{{ABSTRACT_PUBMED_22349229}}
 
==About this Structure==
[[3sx7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SX7 OCA].
 
==Reference==
<ref group="xtra">PMID:022349229</ref><references group="xtra"/>
[[Category: Fucosylgalactoside 3-alpha-galactosyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Evans, S V.]]
[[Category: Large Structures]]
[[Category: Johal, A R.]]
[[Category: Evans SV]]
[[Category: Abo rossmann fold]]
[[Category: Johal AR]]
[[Category: Blood group antigen]]
[[Category: Glycoprotein]]
[[Category: Manganese]]
[[Category: Metal-binding]]
[[Category: Retaining glycosyltransferase]]
[[Category: Transferase]]