3sfp: Difference between revisions

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[[Image:3sfp.png|left|200px]]


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==Crystal Structure of the Mono-Zinc-boundform of New Delhi Metallo-beta-Lactamase-1 from Klebsiella pneumoniae==
The line below this paragraph, containing "STRUCTURE_3sfp", creates the "Structure Box" on the page.
<StructureSection load='3sfp' size='340' side='right'caption='[[3sfp]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3sfp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SFP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3sfp|  PDB=3sfp  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfp OCA], [https://pdbe.org/3sfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sfp RCSB], [https://www.ebi.ac.uk/pdbsum/3sfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfp ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of the Mono-Zinc-boundform of New Delhi Metallo-beta-Lactamase-1 from Klebsiella pneumoniae===
== Function ==
 
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
 
<!--
The line below this paragraph, {{ABSTRACT_PUBMED_21931780}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 21931780 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21931780}}
 
==About this Structure==
[[3sfp]] is a 4 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFP OCA].  


==See Also==
==See Also==
*[[Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021931780</ref><references group="xtra"/>
[[Category: Beta-lactamase]]
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
[[Category: Babnigg, J.]]
[[Category: Large Structures]]
[[Category: Binkowski, T A.]]
[[Category: Babnigg J]]
[[Category: Jedrzejczak, R.]]
[[Category: Binkowski TA]]
[[Category: Joachimiak, A.]]
[[Category: Jedrzejczak R]]
[[Category: Kim, Y.]]
[[Category: Joachimiak A]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Kim Y]]
[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors.]]
[[Category: Tesar C]]
[[Category: Tesar, C.]]
[[Category: Alpha-beta-beta-alpha sandwich]]
[[Category: Hydrolase]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Mtbi]]
[[Category: Periplasmic]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
[[Category: Structures of mtb proteins conferring susceptibility to known mtb inhibitor]]

Latest revision as of 12:55, 14 March 2024

Crystal Structure of the Mono-Zinc-boundform of New Delhi Metallo-beta-Lactamase-1 from Klebsiella pneumoniae

3sfp, resolution 2.27Å

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