3v11: Difference between revisions

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[[Image:3v11.png|left|200px]]


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==Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA==
The line below this paragraph, containing "STRUCTURE_3v11", creates the "Structure Box" on the page.
<StructureSection load='3v11' size='340' side='right'caption='[[3v11]], [[Resolution|resolution]] 5.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3v11]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V11 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene></td></tr>
{{STRUCTURE_3v11|  PDB=3v11  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v11 OCA], [https://pdbe.org/3v11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v11 RCSB], [https://www.ebi.ac.uk/pdbsum/3v11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v11 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]


===Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA===
==See Also==
 
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
 
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</StructureSection>
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{{ABSTRACT_PUBMED_22447243}}
 
==About this Structure==
[[3v11]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V11 OCA].
 
==Reference==
<ref group="xtra">PMID:022447243</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Sulfolobus solfataricus]]
[[Category: Large Structures]]
[[Category: Mechulam, Y.]]
[[Category: Saccharolobus solfataricus P2]]
[[Category: Schmitt, E.]]
[[Category: Mechulam Y]]
[[Category: Gtp and trna]]
[[Category: Schmitt E]]
[[Category: Gtp binding module]]
[[Category: Initiator trna carrier]]
[[Category: Translation-rna complex]]

Latest revision as of 14:14, 14 March 2024

Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA

3v11, resolution 5.00Å

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