2k8m: Difference between revisions

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[[Image:2k8m.png|left|200px]]


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==S100A13-C2A binary complex structure==
The line below this paragraph, containing "STRUCTURE_2k8m", creates the "Structure Box" on the page.
<StructureSection load='2k8m' size='340' side='right'caption='[[2k8m]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2k8m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K8M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k8m OCA], [https://pdbe.org/2k8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k8m RCSB], [https://www.ebi.ac.uk/pdbsum/2k8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k8m ProSAT]</span></td></tr>
{{STRUCTURE_2k8m| PDB=2k8m |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYT1_HUMAN SYT1_HUMAN] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/2k8m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k8m ConSurf].
<div style="clear:both"></div>


===S100A13-C2A binary complex structure===
==See Also==
 
*[[S100 proteins 3D structures|S100 proteins 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_19284995}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 19284995 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_19284995}}
 
==About this Structure==
[[2k8m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K8M OCA].
 
==Reference==
<ref group="xtra">PMID:019284995</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kumar, S M.]]
[[Category: Large Structures]]
[[Category: Mohan, S K.]]
[[Category: Kumar SM]]
[[Category: Rani, S G.]]
[[Category: Mohan SK]]
[[Category: Yu, C.]]
[[Category: Rani SG]]
[[Category: C2a]]
[[Category: Yu C]]
[[Category: Protein transport]]
[[Category: Protein-protein complex]]
[[Category: S100a13]]

Latest revision as of 06:44, 1 May 2024

S100A13-C2A binary complex structure

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