3q0w: Difference between revisions

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[[Image:3q0w.png|left|200px]]


<!--
==ETHR From mycobacterium tuberculosis in complex with compound BDM33066==
The line below this paragraph, containing "STRUCTURE_3q0w", creates the "Structure Box" on the page.
<StructureSection load='3q0w' size='340' side='right'caption='[[3q0w]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3q0w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0W FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LL5:(2S)-2-AMINO-3-METHYL-1-{4-[3-(THIOPHEN-2-YL)-1,2,4-OXADIAZOL-5-YL]PIPERIDIN-1-YL}BUTAN-1-ONE'>LL5</scene></td></tr>
{{STRUCTURE_3q0w|  PDB=3q0w  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0w OCA], [https://pdbe.org/3q0w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0w RCSB], [https://www.ebi.ac.uk/pdbsum/3q0w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0w ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>


===ETHR From mycobacterium tuberculosis in complex with compound BDM33066===
==See Also==
 
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_22156370}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 22156370 is the PubMed ID number.
</StructureSection>
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_22156370}}
 
==About this Structure==
[[3q0w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0W OCA].
 
==Reference==
<ref group="xtra">PMID:022156370</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Baulard, A.]]
[[Category: Baulard A]]
[[Category: Brodin, P.]]
[[Category: Brodin P]]
[[Category: Carette, X.]]
[[Category: Carette X]]
[[Category: Christophe, T.]]
[[Category: Christophe T]]
[[Category: Demirkaya, F.]]
[[Category: Demirkaya F]]
[[Category: Deprez, B.]]
[[Category: Deprez B]]
[[Category: Desrose, M.]]
[[Category: Desrose M]]
[[Category: Dirie, B.]]
[[Category: Dirie B]]
[[Category: Flipo, M.]]
[[Category: Flipo M]]
[[Category: Jeon, H K.]]
[[Category: Jeon HK]]
[[Category: Lens, Z.]]
[[Category: Lens Z]]
[[Category: Leroux, F.]]
[[Category: Leroux F]]
[[Category: Locht, C.]]
[[Category: Locht C]]
[[Category: Piveteau, C.]]
[[Category: Piveteau C]]
[[Category: Rucktooa, P.]]
[[Category: Rucktooa P]]
[[Category: Villeret, V.]]
[[Category: Villeret V]]
[[Category: Willand, N.]]
[[Category: Willand N]]
[[Category: Tetr family]]
[[Category: Transcription-transcription inhibitor complex]]
[[Category: Transcriptional repressor]]

Latest revision as of 10:45, 21 February 2024

ETHR From mycobacterium tuberculosis in complex with compound BDM33066

3q0w, resolution 1.60Å

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