3uom: Difference between revisions

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[[Image:3uom.png|left|200px]]


<!--
==Ca2+ complex of Human skeletal calsequestrin==
The line below this paragraph, containing "STRUCTURE_3uom", creates the "Structure Box" on the page.
<StructureSection load='3uom' size='340' side='right'caption='[[3uom]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3uom]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UOM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
{{STRUCTURE_3uom|  PDB=3uom  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uom OCA], [https://pdbe.org/3uom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uom RCSB], [https://www.ebi.ac.uk/pdbsum/3uom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uom ProSAT]</span></td></tr>
 
</table>
===Ca2+ complex of Human skeletal calsequestrin===
== Function ==
 
[https://www.uniprot.org/uniprot/CASQ1_HUMAN CASQ1_HUMAN] Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction.<ref>PMID:22337878</ref> <ref>PMID:22337878</ref>  
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_22337878}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 22337878 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_22337878}}
 
==About this Structure==
[[3uom]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UOM OCA].  
 
==Reference==
<ref group="xtra">PMID:022337878</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Danna, B R.]]
[[Category: Large Structures]]
[[Category: Kang, C H.]]
[[Category: Danna BR]]
[[Category: Lewis, K M.]]
[[Category: Kang CH]]
[[Category: Nissen, M S.]]
[[Category: Lewis KM]]
[[Category: Sanchez, E J.]]
[[Category: Nissen MS]]
[[Category: Calcium binding]]
[[Category: Sanchez EJ]]
[[Category: Calcium-binding protein]]
[[Category: Sarcoplasmic reticulum]]
[[Category: Thioredoxin-like fold]]

Latest revision as of 14:04, 14 March 2024

Ca2+ complex of Human skeletal calsequestrin

3uom, resolution 2.02Å

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