3vc2: Difference between revisions

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[[Image:3vc2.png|left|200px]]


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==Crystal structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor A3(2) in complex with Mg2+, geranyl diphosphate, and S-adenosyl-L-homocysteine==
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<StructureSection load='3vc2' size='340' side='right'caption='[[3vc2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3vc2]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VC2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.046&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GPP:GERANYL+DIPHOSPHATE'>GPP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3vc2|  PDB=3vc2  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vc2 OCA], [https://pdbe.org/3vc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vc2 RCSB], [https://www.ebi.ac.uk/pdbsum/3vc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vc2 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor A3(2) in complex with Mg2+, geranyl diphosphate, and S-adenosyl-L-homocysteine===
== Function ==
 
[https://www.uniprot.org/uniprot/GPPMT_STRCO GPPMT_STRCO] Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).<ref>PMID:18563898</ref>
 
== References ==
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_22455498}}
[[Category: Christianson DW]]
 
[[Category: Koksal M]]
==About this Structure==
[[3vc2]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VC2 OCA].  
 
==Reference==
<ref group="xtra">PMID:022455498</ref><references group="xtra"/>
[[Category: Streptomyces coelicolor]]
[[Category: Christianson, D W.]]
[[Category: Koksal, M.]]
[[Category: 2-methylisoborneol biosynthesis]]
[[Category: C-methyltransferase]]
[[Category: Methyltransferase fold]]
[[Category: Rossmann fold]]
[[Category: Sam-dependent methyltransferase]]
[[Category: Terpenoid biosynthesis]]
[[Category: Transferase]]