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[[Image:4ea0.jpg|left|200px]]


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==Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651==
The line below this paragraph, containing "STRUCTURE_4ea0", creates the "Structure Box" on the page.
<StructureSection load='4ea0' size='340' side='right'caption='[[4ea0]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4ea0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EA0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=651:(3R)-3-BIPHENYL-4-YL-1-AZABICYCLO[2.2.2]OCTAN-3-OL'>651</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
{{STRUCTURE_4ea0|  PDB=4ea0  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ea0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ea0 OCA], [https://pdbe.org/4ea0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ea0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ea0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ea0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CRTM_STAAU CRTM_STAAU]


===Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651===
==See Also==
 
*[[Squalene synthase|Squalene synthase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4ea0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EA0 OCA].
[[Category: Large Structures]]
[[Category: 4,4'-diapophytoene synthase]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Lin, F Y.]]
[[Category: Lin F-Y]]
[[Category: Liu, Y L.]]
[[Category: Liu Y-L]]
[[Category: Oldfield, E.]]
[[Category: Oldfield E]]
[[Category: Quinuclidine inhibitor]]
[[Category: Transferase-transferase inhibitor complex]]

Latest revision as of 11:02, 1 March 2024

Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651

4ea0, resolution 2.12Å

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