3v9k: Difference between revisions

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[[Image:3v9k.jpg|left|200px]]


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==Crystal structure of mouse 1-pyrroline-5-carboxylate dehydrogenase complexed with the product glutamate==
The line below this paragraph, containing "STRUCTURE_3v9k", creates the "Structure Box" on the page.
<StructureSection load='3v9k' size='340' side='right'caption='[[3v9k]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3v9k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V9K FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.501&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_3v9k|  PDB=3v9k  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v9k OCA], [https://pdbe.org/3v9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v9k RCSB], [https://www.ebi.ac.uk/pdbsum/3v9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v9k ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AL4A1_MOUSE AL4A1_MOUSE] Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity).


===Crystal structure of mouse 1-pyrroline-5-carboxylate dehydrogenase complexed with the product glutamate===
==See Also==
 
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
 
*[[Pyrroline-5-carboxylate dehydrogenase|Pyrroline-5-carboxylate dehydrogenase]]
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22516612}}
 
==About this Structure==
[[3v9k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V9K OCA].
 
==Reference==
<ref group="xtra">PMID:022516612</ref><references group="xtra"/>
[[Category: 1-pyrroline-5-carboxylate dehydrogenase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Srivastava, D.]]
[[Category: Srivastava D]]
[[Category: Tanner, J J.]]
[[Category: Tanner JJ]]
[[Category: Acting on aldehyde or oxo group of donor]]
[[Category: Aldehyde dehydrogenase]]
[[Category: Mitochondria]]
[[Category: Nad or nadp as acceptor]]
[[Category: Nucleotide binding]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]