4eb4: Difference between revisions

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[[Image:4eb4.jpg|left|200px]]


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==Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex==
The line below this paragraph, containing "STRUCTURE_4eb4", creates the "Structure Box" on the page.
<StructureSection load='4eb4' size='340' side='right'caption='[[4eb4]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4eb4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EB4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EB4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
{{STRUCTURE_4eb4|  PDB=4eb4  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eb4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eb4 OCA], [https://pdbe.org/4eb4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eb4 RCSB], [https://www.ebi.ac.uk/pdbsum/4eb4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eb4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).


===Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex===
==See Also==
 
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4eb4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EB4 OCA].
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Thymidylate synthase]]
[[Category: Dowiercial A]]
[[Category: Dowiercial, A.]]
[[Category: Jarmula A]]
[[Category: Jarmula, A.]]
[[Category: Rode W]]
[[Category: Rode, W.]]
[[Category: Rypniewski WR]]
[[Category: Rypniewski, W R.]]
[[Category: Wilk P]]
[[Category: Wilk, P.]]
[[Category: Methyltransferase]]
[[Category: Nucleotide biosynthesis]]
[[Category: Ternary complex]]
[[Category: Transferase]]

Latest revision as of 11:02, 1 March 2024

Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex

4eb4, resolution 1.74Å

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