4f1p: Difference between revisions
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New page: '''Unreleased structure''' The entry 4f1p is ON HOLD Authors: Sun, Fei, Pang, Xiaoyun, Zhang, Kai, Ma, Jun, Zhou,Qiangjun Description: Crystal Structure of mutant S554D for ArfGAP and ... |
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==Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1== | |||
<StructureSection load='4f1p' size='340' side='right'caption='[[4f1p]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4f1p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F1P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f1p OCA], [https://pdbe.org/4f1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f1p RCSB], [https://www.ebi.ac.uk/pdbsum/4f1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f1p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ma J]] | |||
[[Category: Pang X]] | |||
[[Category: Sun F]] | |||
[[Category: Zhang K]] | |||
[[Category: Zhou Q]] | |||
Latest revision as of 08:50, 20 March 2024
Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1
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