3v34: Difference between revisions

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[[Image:3v34.jpg|left|200px]]


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==Crystal structure of MCPIP1 conserved domain with magnesium ion in the catalytic center==
The line below this paragraph, containing "STRUCTURE_3v34", creates the "Structure Box" on the page.
<StructureSection load='3v34' size='340' side='right'caption='[[3v34]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3v34]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V34 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.003&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3v34|  PDB=3v34  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v34 OCA], [https://pdbe.org/3v34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v34 RCSB], [https://www.ebi.ac.uk/pdbsum/3v34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v34 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZC12A_HUMAN ZC12A_HUMAN] Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.<ref>PMID:16574901</ref> <ref>PMID:18364357</ref> <ref>PMID:22561375</ref>  


===Crystal structure of MCPIP1 conserved domain with magnesium ion in the catalytic center===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 22561375 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_22561375}}
 
==About this Structure==
[[3v34]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V34 OCA].
 
==Reference==
<ref group="xtra">PMID:022561375</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Gao, G.]]
[[Category: Large Structures]]
[[Category: Li, X.]]
[[Category: Gao G]]
[[Category: Peng, W.]]
[[Category: Li X]]
[[Category: Rao, Z.]]
[[Category: Peng W]]
[[Category: Sun, Y.]]
[[Category: Rao Z]]
[[Category: Wang, X.]]
[[Category: Sun Y]]
[[Category: Xu, J.]]
[[Category: Wang X]]
[[Category: Xu, Y.]]
[[Category: Xu J]]
[[Category: Cytoplastic]]
[[Category: Xu Y]]
[[Category: Hydrolase]]
[[Category: Rnase]]
[[Category: Rossmann-like sandwich fold]]
Retrieved from "https://proteopedia.org/3v34"