4esr: Difference between revisions

(6 intermediate revisions by the same user not shown)

Line 1:

~~'''Unreleased structure'''~~

~~The entry 4esr is ON HOLD until Paper Publication~~

==Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors==

~~Authors: Van Petegem, X.F., Liu, P.X., Lobo, P., Jiang, X.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4esr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESR OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4ESR FirstGlance].

~~Description:~~ Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4esr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esr OCA], [https://pdbe.org/4esr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4esr RCSB], [https://www.ebi.ac.uk/pdbsum/4esr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4esr ProSAT]</td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/AHI1_HUMAN AHI1_HUMAN] Joubert syndrome;Joubert syndrome with ocular defect. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/AHI1_HUMAN AHI1_HUMAN] Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Jiang X]]

[[Category: Liu PX]]

[[Category: Lobo P]]

[[Category: Van Petegem XF]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4esr is ON HOLD  until Paper Publication
+==Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors==
+<StructureSection load='4esr' size='340' side='right'caption='[[4esr]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
-Authors: Van Petegem, X.F., Liu, P.X., Lobo, P., Jiang, X.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4esr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ESR FirstGlance]. <br>
-Description: Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4esr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esr OCA], [https://pdbe.org/4esr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4esr RCSB], [https://www.ebi.ac.uk/pdbsum/4esr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4esr ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/AHI1_HUMAN AHI1_HUMAN] Joubert syndrome;Joubert syndrome with ocular defect. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/AHI1_HUMAN AHI1_HUMAN] Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Jiang X]]
+[[Category: Liu PX]]
+[[Category: Lobo P]]
+[[Category: Van Petegem XF]]