4eox: Difference between revisions

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[[Image:4eox.jpg|left|200px]]


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==X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor==
The line below this paragraph, containing "STRUCTURE_4eox", creates the "Structure Box" on the page.
<StructureSection load='4eox' size='340' side='right'caption='[[4eox]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EOX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.783&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
{{STRUCTURE_4eox|  PDB=4eox  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [https://pdbe.org/4eox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [https://www.ebi.ac.uk/pdbsum/4eox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eox ProSAT]</span></td></tr>
 
</table>
===X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor===
== Function ==
 
[https://www.uniprot.org/uniprot/DEF_STRR6 DEF_STRR6] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_22579486}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 22579486 is the PubMed ID number.
[[Category: Streptococcus pneumoniae R6]]
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[[Category: Campobasso N]]
{{ABSTRACT_PUBMED_22579486}}
[[Category: Ward P]]
 
==About this Structure==
[[4eox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA].  
 
==Reference==
<ref group="xtra">PMID:022579486</ref><references group="xtra"/>
[[Category: Peptide deformylase]]
[[Category: Streptococcus pneumoniae]]
[[Category: Campobasso, N.]]
[[Category: Ward, P.]]
[[Category: Alpha-beta]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Peptide deformylase metal ion binding]]
Retrieved from "https://proteopedia.org/4eox"