4egl: Difference between revisions

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[[Image:4egl.jpg|left|200px]]


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==Crystal structure of two tandem RNA recognition motifs of Human antigen R==
The line below this paragraph, containing "STRUCTURE_4egl", creates the "Structure Box" on the page.
<StructureSection load='4egl' size='340' side='right'caption='[[4egl]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4egl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EGL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_4egl|  PDB=4egl  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4egl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4egl OCA], [https://pdbe.org/4egl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4egl RCSB], [https://www.ebi.ac.uk/pdbsum/4egl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4egl ProSAT]</span></td></tr>
 
</table>
===Crystal structure of two tandem RNA recognition motifs of Human antigen R===
== Function ==
 
[https://www.uniprot.org/uniprot/ELAV1_HUMAN ELAV1_HUMAN] Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro.<ref>PMID:19029303</ref>
 
== References ==
==About this Structure==
<references/>
[[4egl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EGL OCA].  
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Li, X.]]
[[Category: Large Structures]]
[[Category: Liu, H.]]
[[Category: Li X]]
[[Category: Teng, M.]]
[[Category: Liu H]]
[[Category: Wang, H.]]
[[Category: Teng M]]
[[Category: Zeng, F.]]
[[Category: Wang H]]
[[Category: Cytoplasm and nucleus]]
[[Category: Zeng F]]
[[Category: Rna binding]]
[[Category: Rna binding protein]]
[[Category: Rrm]]
Retrieved from "https://proteopedia.org/4egl"