3dwr: Difference between revisions

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[[Image:3dwr.png|left|200px]]


<!--
==Leishmania major coproporphyrinogen III oxidase with bound ligand==
The line below this paragraph, containing "STRUCTURE_3dwr", creates the "Structure Box" on the page.
<StructureSection load='3dwr' size='340' side='right'caption='[[3dwr]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3dwr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DWR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PA:CYCLOPENTYLACETIC+ACID'>0PA</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
{{STRUCTURE_3dwr|  PDB=3dwr  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dwr OCA], [https://pdbe.org/3dwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dwr RCSB], [https://www.ebi.ac.uk/pdbsum/3dwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dwr ProSAT]</span></td></tr>
 
</table>
===Leishmania major coproporphyrinogen III oxidase with bound ligand===
== Function ==
 
[https://www.uniprot.org/uniprot/HEM6_LEIMA HEM6_LEIMA] Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).[HAMAP-Rule:MF_00333]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[3dwr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DWR OCA].  
Check<jmol>
[[Category: Coproporphyrinogen oxidase]]
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dw/3dwr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dwr ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania major]]
[[Category: Leishmania major]]
[[Category: Merritt, E A.]]
[[Category: Le Trong I]]
[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
[[Category: Merritt EA]]
[[Category: Trong, I Le.]]
[[Category: Fragment cocktail]]
[[Category: Heme biosynthesis]]
[[Category: Oxidoreductase]]
[[Category: Porphyrin biosynthesis]]
[[Category: Sgpp]]
[[Category: Structural genomic]]
[[Category: Structural genomics of pathogenic protozoa consortium]]
Retrieved from "https://proteopedia.org/3dwr"