2w7t: Difference between revisions

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<!--
==Trypanosoma brucei CTPS - glutaminase domain with bound acivicin==
The line below this paragraph, containing "STRUCTURE_2w7t", creates the "Structure Box" on the page.
<StructureSection load='2w7t' size='340' side='right'caption='[[2w7t]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2w7t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W7T FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CS:2-AMINO-3-(CYSTEIN-S-YL)-ISOXAZOLIDIN-5-YL-ACETIC+ACID'>5CS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
{{STRUCTURE_2w7t|  PDB=2w7t  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7t OCA], [https://pdbe.org/2w7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w7t RCSB], [https://www.ebi.ac.uk/pdbsum/2w7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7t ProSAT]</span></td></tr>
 
</table>
===TRYPANOSOMA BRUCEI CTPS - GLUTAMINASE DOMAIN WITH BOUND ACIVICIN===
== Function ==
 
[https://www.uniprot.org/uniprot/Q4GZ95_TRYB2 Q4GZ95_TRYB2] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.[RuleBase:RU810713]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[2w7t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7T OCA].  
Check<jmol>
[[Category: CTP synthase]]
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w7t ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Berg, S Van Den.]]
[[Category: Berglund H]]
[[Category: Berglund, H.]]
[[Category: Bountra C]]
[[Category: Bountra, C.]]
[[Category: Collins R]]
[[Category: Collins, R.]]
[[Category: Dahlgren LG]]
[[Category: Consortium, Structural Genomics.]]
[[Category: Edwards AM]]
[[Category: Dahlgren, L G.]]
[[Category: Flodin S]]
[[Category: Edwards, A M.]]
[[Category: Flores A]]
[[Category: Flodin, S.]]
[[Category: Graslund S]]
[[Category: Flores, A.]]
[[Category: Hammarstrom M]]
[[Category: Graslund, S.]]
[[Category: Johansson A]]
[[Category: Hammarstrom, M.]]
[[Category: Johansson I]]
[[Category: Johansson, A.]]
[[Category: Karlberg T]]
[[Category: Johansson, I.]]
[[Category: Kotenyova T]]
[[Category: Karlberg, T.]]
[[Category: Lehtio L]]
[[Category: Kotenyova, T.]]
[[Category: Moche M]]
[[Category: Lehtio, L.]]
[[Category: Nilsson ME]]
[[Category: Moche, M.]]
[[Category: Nordlund P]]
[[Category: Nilsson, M E.]]
[[Category: Nyman T]]
[[Category: Nordlund, P.]]
[[Category: Persson C]]
[[Category: Nyman, T.]]
[[Category: Sagemark J]]
[[Category: Persson, C.]]
[[Category: Schueler H]]
[[Category: Sagemark, J.]]
[[Category: Siponen MI]]
[[Category: Schueler, H.]]
[[Category: Thorsell AG]]
[[Category: Siponen, M I.]]
[[Category: Tresaugues L]]
[[Category: Thorsell, A G.]]
[[Category: Van Den Berg S]]
[[Category: Tresaugues, L.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Welin M]]
[[Category: Welin, M.]]
[[Category: Wikstrom M]]
[[Category: Wikstrom, M.]]
[[Category: Wisniewska M]]
[[Category: Wisniewska, M.]]
[[Category: Acivicin]]
[[Category: Ctp synthetase]]
[[Category: Ctp]]
[[Category: Glutaminase domain]]
[[Category: Ligase]]
[[Category: Trypsanosoma brucei]]

Latest revision as of 15:47, 13 December 2023

Trypanosoma brucei CTPS - glutaminase domain with bound acivicin

2w7t, resolution 2.10Å

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