1fx2: Difference between revisions

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[[Image:1fx2.png|left|200px]]


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==STRUCTURAL ANALYSIS OF ADENYLATE CYCLASES FROM TRYPANOSOMA BRUCEI IN THEIR MONOMERIC STATE==
The line below this paragraph, containing "STRUCTURE_1fx2", creates the "Structure Box" on the page.
<StructureSection load='1fx2' size='340' side='right'caption='[[1fx2]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fx2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FX2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1fx2|  PDB=1fx2  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fx2 OCA], [https://pdbe.org/1fx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fx2 RCSB], [https://www.ebi.ac.uk/pdbsum/1fx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fx2 ProSAT]</span></td></tr>
 
</table>
===STRUCTURAL ANALYSIS OF ADENYLATE CYCLASES FROM TRYPANOSOMA BRUCEI IN THEIR MONOMERIC STATE===
== Function ==
 
[https://www.uniprot.org/uniprot/CY41_TRYBB CY41_TRYBB] Could act as a receptor for an unknown ligand.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_11157750}}, adds the Publication Abstract to the page
Check<jmol>
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  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fx/1fx2_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11157750}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1fx2]] is a 1 chain structure of [[Adenylyl cyclase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX2 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fx2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Adenylyl cyclase|Adenylyl cyclase]]
*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:011157750</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Adenylate cyclase]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
[[Category: Bieger, B.]]
[[Category: Bieger B]]
[[Category: Essen, L O.]]
[[Category: Essen L-O]]
[[Category: Adenylyl cyclase]]
[[Category: Camp]]
[[Category: Catalysis]]
[[Category: Lyase]]
[[Category: Monomer-dimer]]
[[Category: Trypanosome]]
Retrieved from "https://proteopedia.org/1fx2"