3c61: Difference between revisions

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<!--
==Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani==
The line below this paragraph, containing "STRUCTURE_3c61", creates the "Structure Box" on the page.
<StructureSection load='3c61' size='340' side='right'caption='[[3c61]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3c61]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C61 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTU:(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL'>DTU</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr>
{{STRUCTURE_3c61| PDB=3c61 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c61 OCA], [https://pdbe.org/3c61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c61 RCSB], [https://www.ebi.ac.uk/pdbsum/3c61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c61 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D0VWT2_LEIDO D0VWT2_LEIDO] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.[RuleBase:RU364042]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c6/3c61_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c61 ConSurf].
<div style="clear:both"></div>


===Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani===
==See Also==
 
*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3c61]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C61 OCA].
[[Category: Large Structures]]
[[Category: Dihydroorotate dehydrogenase]]
[[Category: Leishmania donovani]]
[[Category: Leishmania donovani]]
[[Category: Arakaki, T L.]]
[[Category: Arakaki TL]]
[[Category: Merritt, E A.]]
[[Category: Merritt EA]]
[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
[[Category: Dihydroorotate dehydrogenase]]
[[Category: Leishmaniasis]]
[[Category: Oxidoreductase]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Sgpp]]
[[Category: Structural genomic]]
[[Category: Structural genomics of pathogenic protozoa consortium]]

Latest revision as of 12:22, 30 August 2023

Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani

3c61, resolution 1.80Å

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