1n4n: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
New page: left|200px <!-- The line below this paragraph, containing "STRUCTURE_1n4n", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1n4n.png|left|200px]]


<!--
==Structure of the Plant Defensin PhD1 from Petunia Hybrida==
The line below this paragraph, containing "STRUCTURE_1n4n", creates the "Structure Box" on the page.
<StructureSection load='1n4n' size='340' side='right'caption='[[1n4n]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1n4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Petunia_x_hybrida Petunia x hybrida]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N4N FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n4n OCA], [https://pdbe.org/1n4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n4n RCSB], [https://www.ebi.ac.uk/pdbsum/1n4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n4n ProSAT]</span></td></tr>
{{STRUCTURE_1n4n|  PDB=1n4n  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEF1_PETHY DEF1_PETHY] Plant defense peptide with antifungal activity against F.oxysporum and B.cinerea.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n4/1n4n_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n4n ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The structure of a novel plant defensin isolated from the flowers of Petunia hybrida has been determined by (1)H NMR spectroscopy. P. hybrida defensin 1 (PhD1) is a basic, cysteine-rich, antifungal protein of 47 residues and is the first example of a new subclass of plant defensins with five disulfide bonds whose structure has been determined. PhD1 has the fold of the cysteine-stabilized alphabeta motif, consisting of an alpha-helix and a triple-stranded antiparallel beta-sheet, except that it contains a fifth disulfide bond from the first loop to the alpha-helix. The additional disulfide bond is accommodated in PhD1 without any alteration of its tertiary structure with respect to other plant defensins. Comparison of its structure with those of classic, four-disulfide defensins has allowed us to identify a previously unrecognized hydrogen bond network that is integral to structure stabilization in the family.


===Structure of the Plant Defensin PhD1 from Petunia Hybrida===
Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds.,Janssen BJ, Schirra HJ, Lay FT, Anderson MA, Craik DJ Biochemistry. 2003 Jul 15;42(27):8214-22. PMID:12846570<ref>PMID:12846570</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1n4n" style="background-color:#fffaf0;"></div>


<!--
==See Also==
The line below this paragraph, {{ABSTRACT_PUBMED_12846570}}, adds the Publication Abstract to the page
*[[Plant defensin|Plant defensin]]
(as it appears on PubMed at http://www.pubmed.gov), where 12846570 is the PubMed ID number.
== References ==
-->
<references/>
{{ABSTRACT_PUBMED_12846570}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[1n4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Petunia_x_hybrida Petunia x hybrida]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4N OCA].
 
==Reference==
<ref group="xtra">PMID:012846570</ref><references group="xtra"/>
[[Category: Petunia x hybrida]]
[[Category: Petunia x hybrida]]
[[Category: Anderson, M A.]]
[[Category: Anderson MA]]
[[Category: Craik, D J.]]
[[Category: Craik DJ]]
[[Category: Janssen, B J.C.]]
[[Category: Janssen BJC]]
[[Category: Lay, F T.]]
[[Category: Lay FT]]
[[Category: Schirra, H J.]]
[[Category: Schirra HJ]]
[[Category: Cysteine-stabilised alpha-beta motif]]
[[Category: Fifth disulfide bond]]
[[Category: Plant protein]]

Latest revision as of 04:44, 17 October 2024

Structure of the Plant Defensin PhD1 from Petunia Hybrida

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1n4n&oldid=4223728"