3m3w: Difference between revisions

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[[Image:3m3w.png|left|200px]]


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==Crystal structure of mouse PACSIN3 BAR domain mutant==
The line below this paragraph, containing "STRUCTURE_3m3w", creates the "Structure Box" on the page.
<StructureSection load='3m3w' size='340' side='right'caption='[[3m3w]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3m3w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M3W FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m3w OCA], [https://pdbe.org/3m3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m3w RCSB], [https://www.ebi.ac.uk/pdbsum/3m3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m3w ProSAT]</span></td></tr>
{{STRUCTURE_3m3w|  PDB=3m3w  |  SCENE=  }}
</table>
 
== Function ==
===Crystal strcuture of mouse PACSIN3 BAR domain mutant===
[https://www.uniprot.org/uniprot/PACN3_MOUSE PACN3_MOUSE] Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
 
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22573331 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22573331}}
 
==About this Structure==
[[3m3w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M3W OCA].  
 
==Reference==
<ref group="xtra">PMID:022573331</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Bai, X Y.]]
[[Category: Bai XY]]
[[Category: Meng, G.]]
[[Category: Meng G]]
[[Category: Bar domain]]
[[Category: Endocytosis]]
[[Category: Mouse]]
[[Category: Pacsin3]]

Latest revision as of 08:31, 20 March 2024

Crystal structure of mouse PACSIN3 BAR domain mutant

3m3w, resolution 2.60Å

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