3rum: Difference between revisions

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[[Image:3rum.jpg|left|200px]]


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==New strategy to analyze structures of glycopeptide antibiotic-target complexes==
The line below this paragraph, containing "STRUCTURE_3rum", creates the "Structure Box" on the page.
<StructureSection load='3rum' size='340' side='right'caption='[[3rum]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rum]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_lurida Amycolatopsis lurida] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RUM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.851&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BXY:ALPHA-D-ARABINOFURANOSE'>BXY</scene>, <scene name='pdbligand=CCS:CARBOXYMETHYLATED+CYSTEINE'>CCS</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=GHP:(2R)-AMINO(4-HYDROXYPHENYL)ETHANOIC+ACID'>GHP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=HTY:(BETAR)-BETA-HYDROXY-D-TYROSINE'>HTY</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MDF:META,+META-DI-HYDROXY-PHENYLALANINE'>MDF</scene>, <scene name='pdbligand=MP4:(2S)-AMINO(3,5-DIHYDROXY-4-METHYLPHENYL)ETHANOIC+ACID'>MP4</scene>, <scene name='pdbligand=OMX:(BETAR)-BETA-HYDROXY-L-TYROSINE'>OMX</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene>, <scene name='pdbligand=RAM:ALPHA-L-RHAMNOSE'>RAM</scene>, <scene name='pdbligand=RST:RISTOSAMINE'>RST</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3rum|  PDB=3rum  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rum OCA], [https://pdbe.org/3rum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rum RCSB], [https://www.ebi.ac.uk/pdbsum/3rum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rum ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.


===New strategy to analyze structures of glycopeptide antibiotic-target complexes===
==See Also==
 
*[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]]
 
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{{ABSTRACT_PUBMED_22352468}}
 
==About this Structure==
[[3rum]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_lurida Amycolatopsis lurida] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RUM OCA].
 
==Reference==
<ref group="xtra">PMID:022352468</ref><references group="xtra"/>
[[Category: Amycolatopsis lurida]]
[[Category: Amycolatopsis lurida]]
[[Category: Escherichia coli k-12]]
[[Category: Escherichia coli K-12]]
[[Category: Economou, N J.]]
[[Category: Large Structures]]
[[Category: Grasty, K C.]]
[[Category: Economou NJ]]
[[Category: Loll, P J.]]
[[Category: Grasty KC]]
[[Category: Nahoum, V.]]
[[Category: Loll PJ]]
[[Category: Weeks, S D.]]
[[Category: Nahoum V]]
[[Category: Antibiotic]]
[[Category: Weeks SD]]
[[Category: Carboxymethylation of cysteine]]
[[Category: Fusion]]
[[Category: Glycopeptide]]
[[Category: Native protein ligation]]
[[Category: Ristocetin]]
[[Category: Sugar binding protein-antibiotic complex]]

Latest revision as of 12:38, 14 March 2024

New strategy to analyze structures of glycopeptide antibiotic-target complexes

3rum, resolution 1.85Å

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