3zxc: Difference between revisions

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[[Image:3zxc.jpg|left|200px]]


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==E69 deletion mutant single insulin-like growth factor binding domain protein (SIBD-1) from Cupiennius salei==
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<StructureSection load='3zxc' size='340' side='right'caption='[[3zxc]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3zxc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupiennius_salei Cupiennius salei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZXC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
{{STRUCTURE_3zxc|  PDB=3zxc  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zxc OCA], [https://pdbe.org/3zxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zxc RCSB], [https://www.ebi.ac.uk/pdbsum/3zxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zxc ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Cupiennius salei single insulin-like growth factor binding domain protein (SIBD-1) is an 8.6 kDa Cys-, Pro-, and Gly-rich protein, discovered in the hemocytes of the Central American hunting spider Cupiennius salei. SIBD-1 exhibits high sequence similarity to the N-terminal domain of the insulin-like growth factor-binding protein superfamily and has been reported to play an important role in the spider's immune system. Here, the recombinant expression as well as the elucidation of the three dimensional structure of recombinant SIBD-1 and the characterization of the sugar moiety at Thr2 of native SIBD-1 is described in detail. Proteins 2012. (c) 2012 Wiley-Liss, Inc.


===E69 deletion mutant single insulin-like growth factor binding domain protein (SIBD-1) from Cupiennius salei===
Structural and Biochemical Characterization of Native and Recombinant Single Insulin-like Growth Factor-Binding Domain Protein (SIBD-1) from the Central American Hunting Spider Cupiennius salei (Ctenidae).,Trachsel C, Widmer C, Kampfer U, Buhr C, Baumann T, Kuhn-Nentwig L, Schurch S, Schaller J, Baumann U Proteins. 2012 May 24. doi: 10.1002/prot.24119. PMID:22622866<ref>PMID:22622866</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 3zxc" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 22622866 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_22622866}}
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</StructureSection>
==About this Structure==
[[3zxc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cupiennius_salei Cupiennius salei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXC OCA].
 
==Reference==
<ref group="xtra">PMID:022622866</ref><references group="xtra"/>
[[Category: Cupiennius salei]]
[[Category: Cupiennius salei]]
[[Category: Baumann, U.]]
[[Category: Large Structures]]
[[Category: Widmer, C.]]
[[Category: Baumann U]]
[[Category: Igfbp]]
[[Category: Widmer C]]
[[Category: Signaling]]
[[Category: Single insulin-binding domain]]
Retrieved from "https://proteopedia.org/3zxc"