4esr: Difference between revisions

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[[Image:4esr.jpg|left|200px]]


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==Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors==
The line below this paragraph, containing "STRUCTURE_4esr", creates the "Structure Box" on the page.
<StructureSection load='4esr' size='340' side='right'caption='[[4esr]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4esr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ESR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
{{STRUCTURE_4esr|  PDB=4esr  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4esr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esr OCA], [https://pdbe.org/4esr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4esr RCSB], [https://www.ebi.ac.uk/pdbsum/4esr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4esr ProSAT]</span></td></tr>
 
</table>
===Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors===
== Disease ==
 
[https://www.uniprot.org/uniprot/AHI1_HUMAN AHI1_HUMAN] Joubert syndrome;Joubert syndrome with ocular defect. The disease is caused by mutations affecting the gene represented in this entry.
 
== Function ==
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[https://www.uniprot.org/uniprot/AHI1_HUMAN AHI1_HUMAN] Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.
The line below this paragraph, {{ABSTRACT_PUBMED_22623184}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 22623184 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_22623184}}
 
==About this Structure==
[[4esr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESR OCA].  
 
==Reference==
<ref group="xtra">PMID:022623184</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Jiang, X.]]
[[Category: Large Structures]]
[[Category: Liu, P X.]]
[[Category: Jiang X]]
[[Category: Lobo, P.]]
[[Category: Liu PX]]
[[Category: Petegem, X F.Van.]]
[[Category: Lobo P]]
[[Category: Ahi-1]]
[[Category: Van Petegem XF]]
[[Category: Ahi-1 sh3 domain]]
[[Category: Ahi1]]
[[Category: Chronic myeloid leukemia]]
[[Category: Dynamin-2]]
[[Category: Protein binding]]
[[Category: Sh3 domain]]
Retrieved from "https://proteopedia.org/4esr"