3sa4: Difference between revisions

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[[Image:3sa4.jpg|left|200px]]


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==Crystal structure of wild-type HIV-1 protease in complex with AF72==
The line below this paragraph, containing "STRUCTURE_3sa4", creates the "Structure Box" on the page.
<StructureSection load='3sa4' size='340' side='right'caption='[[3sa4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3sa4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SA4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=F72:N-{(2S,3R)-4-[(1,3-BENZOTHIAZOL-6-YLSULFONYL)(CYCLOHEXYLMETHYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}-3-HYDROXYBENZAMIDE'>F72</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3sa4|  PDB=3sa4  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa4 OCA], [https://pdbe.org/3sa4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sa4 RCSB], [https://www.ebi.ac.uk/pdbsum/3sa4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sa4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O38732_9HIV1 O38732_9HIV1]


===Crystal structure of wild-type HIV-1 protease in complex with AF72===
==See Also==
 
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3sa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA4 OCA].
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Nalam, M N.L.]]
[[Category: Large Structures]]
[[Category: Schiffer, C A.]]
[[Category: Nalam MNL]]
[[Category: Aid]]
[[Category: Schiffer CA]]
[[Category: Aspartyl protease]]
[[Category: Drug design]]
[[Category: Drug resistance]]
[[Category: Hiv-1 protease]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease inhibitor]]

Latest revision as of 12:51, 14 March 2024

Crystal structure of wild-type HIV-1 protease in complex with AF72

3sa4, resolution 1.80Å

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