Kemp elimination catalyst: Difference between revisions
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New page: <StructureSection load='Crdes1.pdb' size='500' frame='true' align='right' scene='3iio/Int/1' > left|200px <!-- The line below this paragraph, containing "STRUCTURE_2rkx"... |
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<StructureSection load='Crdes1.pdb' size=' | <StructureSection load='Crdes1.pdb' size='400' frame='true' side='right' scene='3iio/Int/1' > | ||
[[Image:2rkx.jpg|left|200px]] | [[Image:2rkx.jpg|left|200px]] | ||
===The 3D structure of a designed enzyme that acts as a Kemp elimination catalyst=== | ===The 3D structure of a designed enzyme that acts as a Kemp elimination catalyst=== | ||
(see also [[Directed evolution]], [[3iio]], [[3iip]], and [[3iiv]]) | (see also [[Directed evolution]], [[3iio]], [[3iip]], and [[3iiv]]) | ||
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==About this Structure== | ==About this Structure== | ||
2RKX is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKX OCA]. | 2RKX is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKX OCA]. | ||
==Primary Reference== | ==Primary Reference== | ||
Kemp elimination catalysts by computational enzyme design., Rothlisberger D, Khersonsky O, Wollacott AM, Jiang L, DeChancie J, Betker J, Gallaher JL, Althoff EA, Zanghellini A, Dym O, Albeck S, Houk KN, Tawfik DS, Baker D, Nature. 2008 May 8;453(7192):190-5. Epub 2008 Mar 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18354394 18354394] | Kemp elimination catalysts by computational enzyme design., Rothlisberger D, Khersonsky O, Wollacott AM, Jiang L, DeChancie J, Betker J, Gallaher JL, Althoff EA, Zanghellini A, Dym O, Albeck S, Houk KN, Tawfik DS, Baker D, Nature. 2008 May 8;453(7192):190-5. Epub 2008 Mar 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18354394 18354394] | ||
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[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
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Created with the participation of [[User:Michal Harel|Michal Harel]], [[User:Jaime Prilusky|Jaime Prilusky]], [[User:Eran Hodis|Eran Hodis]]. | Created with the participation of [[User:Michal Harel|Michal Harel]], [[User:Jaime Prilusky|Jaime Prilusky]], [[User:Eran Hodis|Eran Hodis]]. | ||