3t50: Difference between revisions
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==X-ray structure of the LOV domain from the LOV-HK sensory protein from Brucella abortus (dark state).== | |||
<StructureSection load='3t50' size='340' side='right'caption='[[3t50]], [[Resolution|resolution]] 1.64Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3t50]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_melitensis Brucella melitensis]. The March 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T50 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T50 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t50 OCA], [https://pdbe.org/3t50 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t50 RCSB], [https://www.ebi.ac.uk/pdbsum/3t50 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t50 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LOVHK_BRUME LOVHK_BRUME] Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection of the next host. This photoreceptor protein is directly related to the bacterium's survival and replication within host macrophages. | |||
__TOC__ | |||
< | </StructureSection> | ||
== | |||
[[3t50]] is a 2 chain structure with sequence from [ | |||
== | |||
< | |||
[[Category: Brucella melitensis]] | [[Category: Brucella melitensis]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Phototropin]] | ||
[[Category: | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: | [[Category: Goldbaum FA]] | ||
[[Category: | [[Category: Klinke S]] | ||
[[Category: | [[Category: Rinaldi JJ]] | ||
Latest revision as of 13:17, 14 March 2024
X-ray structure of the LOV domain from the LOV-HK sensory protein from Brucella abortus (dark state).
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