4esu: Difference between revisions

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[[Image:4esu.jpg|left|200px]]


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==Crystal structure of rabbit ryanodine receptor 1 mutant S2776M==
The line below this paragraph, containing "STRUCTURE_4esu", creates the "Structure Box" on the page.
<StructureSection load='4esu' size='340' side='right'caption='[[4esu]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4esu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ESU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_4esu|  PDB=4esu  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4esu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esu OCA], [https://pdbe.org/4esu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4esu RCSB], [https://www.ebi.ac.uk/pdbsum/4esu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4esu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RYR1_RABIT RYR1_RABIT] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity).<ref>PMID:10388749</ref> <ref>PMID:22036948</ref>  


===Crystal structure of rabbit ryanodine receptor 1 mutant S2776M===
==See Also==
 
*[[Ryanodine receptor 3D structures|Ryanodine receptor 3D structures]]
 
== References ==
==About this Structure==
<references/>
[[4esu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESU OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Lau, K.]]
[[Category: Lau K]]
[[Category: Petegem, F Van.]]
[[Category: Van Petegem F]]
[[Category: Yuchi, Z.]]
[[Category: Yuchi Z]]
[[Category: Metal transport]]
[[Category: Muscle]]
[[Category: Phosphorylation]]
[[Category: Ryanodine receptor calcium release channel]]
[[Category: Skeletal]]
Retrieved from "https://proteopedia.org/4esu"